Sameera Reddy made her debut in ghazal singer Pankaj Udhas’s music video, “Aahista Aahista”, when she was a graduate. The song was appreciated and her looks were noticed. She earned her ticket to Bollywood with a pivotal role in the Hindi feature film, Maine Dil Tujhko Diya in 2002. She is famous for her role in Musafir.